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In addition, the mechanism by which caspase 8 prevents receptor-interacting protein 1 (RIP1) and RIP3-mediated necroptosis is now an area of great interest. Susan Taylor. Genomic science has changed the way we think about and delivers biology with a new paradigm for asking biological questions and for thinking about evolution.
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studies provided fundamental new insights into epigenetics, clarified the molecular understanding of altered gene regulation in disease, and have enabled fundamental new discoveries such as RNAi and the existence of miRNAs in the genome.
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The last 10 years have been remarkable in terms of our understanding of genome organization, chromatin structure, and gene expression that provide the basis for specifying the function of individual cells. This information also provided the basis for many 8 genome-wide studies monitoring a number of biological processes and disease states